Historical annual and monthly returns for Vertex Pharmaceuticals (VRTX).
For Vertex Pharmaceuticals (VRTX), the strongest completed calendar year was 2000, when the stock returned 308.6%, while its weakest was 2001, with a return of -65.6%. Across the 26 completed calendar years from 2000 through 2025, its average annual return was 28.5% and its compounded annual return was 13.3%. VRTX posted positive returns in 17 of those 26 years (65%). In 2025, the latest completed year, it returned 12.6%. In 2026 year to date, VRTX has returned 16.1%.
Returns are calculated from the adjusted daily closing prices for Vertex Pharmaceuticals (VRTX). Annual returns measure the percentage change between the final available trading prices of consecutive calendar years. Monthly returns use the corresponding month-end observations. Adjusted prices account for stock splits and distributions when supplied by the market-data provider. Results are nominal and are not adjusted for inflation.
